Published June 20, 2025 | Originally published on ScienceAlert Latest

The liver is one of the hardest working organs in the human body. It detoxifies harmful substances, helps with digestion, stores nutrients, and regulates metabolism.Despite its remarkable resilience – and even its ability to regenerate – the liver is not indestructible. In fact, many everyday habits, often overlooked, can slowly cause damage that may eventually lead to serious conditions such as cirrhosis (permanent scarring of the liver) or liver failure.
One of the challenges with liver disease is that it can be a silent threat. In its early stages, it may cause only vague symptoms like constant fatigue or nausea.

As damage progresses, more obvious signs may emerge. One of the most recognisable is jaundice, where the skin and the whites of the eyes turn yellow.
While most people associate liver disease with heavy drinking, alcohol isn't the only culprit.

TO CONTINUE READING:​https://www.mdlinx.com/news/5-daily-habits-could-be-causing-your-liver-serious-harm/4mtIzFD66eIlvvAW0f9ld4?show_order=2&utm_campaign=re

By Bobby McGuireJune 7, 2025 at 7:00am Queerty

While many in the queer community watch stunned in disbelief as anti-LGBTQ+ rhetoric and legislation designed to dismantle transgender healthcare sweeps across America, a gay councilmember in the heart of queer New York City is refusing to stand still.
Erik Bottcher, representing the historic neighborhoods where Stonewall’s legacy lives on, isn’t just posting rainbow flags or offering sympathetic tweets (the queer equivalent of ‘thoughts and prayers’)—he’s wielding legislative power.
As the current administration actively worked in its first weeks to roll back transgender rights through executive orders, Bottcher and his allies on the city’s LGBTQIA+ Caucus were busy on the counteroffensive, creating a bold legislative package designed to safeguard transgender, gender non-conforming, nonbinary, and intersex (TGNCNBI) New York

TO CONTINUE: https://www.queerty.com/nyc-councilmember-erik-bottcher-offers-a-lot-more-than-thoughts-prayers-for-the-queer-community-20250607/

​By Kerry BreenEdited By Kierra FrazierMay 8, 2025 / 5:21 PM EDT / CBS News

The Trump administration has proposed cutting a $56 million grant that teaches first responders how to use the lifesaving overdose reversal drug naloxone, which experts say could reverse progress the United States has made in lowering opioid overdose deaths. 
A recent dip in overdose deaths has been credited in part to wider naloxone access. The medication was made available for over-the-counter purchase in 2023 and is standard for first responders to carry. It's even popped up in some classrooms. 
Naloxone, also sold under the brand name Narcan, is available in injectable and nasal spray form. It is an opioid antagonist that attaches to receptors in the brain, reversing and blocking the effects of other opioids, including fentanyl. 
The grant money can be used by state and local organizations for training people on how to use naloxone, as well as administering and distributing the medication. Grantees are expected to establish protocols to refer patients to treatment or support services and provide other safety information about illicit drugs and overdoses. The grant is administered by the Substance Abuse and Mental Health Services Administration. 
"While some skeptics may think that naloxone - and harm reduction more generally - enable people, there is decades of research that show giving people the information and tools they need helps keep people safe," medical anthropologist Jennifer Syvertsen said in an emailed statement. "Naloxone simply enables people to breathe." 

TO CONTINUE READING::
​https://www.cbsnews.com/news/overdose-deaths-narcan-naloxone-harm-reduction-samhsa-trump-cuts/?fbclid=IwY2xjawKm1U1leHRuA2FlbQIxMQBicmlkETFtTmwySjFJR3RmMXAxM21VAR4Ee7kbQFIDYAwwghR4_JtT9M0yW1g29NSxarRYVRlg8qiuR5_c6gxnhl6fLA_aem_J9UJqxAmR7cS1r0vVO1sDg

Meeting Abstract: 2025 ASCO Gastrointestinal Cancers Symposium
Hepatobiliary Cancer  January 27, 2025
​Authors: Fnu Anamika, Akshit Chitkara, Marciano Figueroa, Arshia Adib, and Rushin PatelAuthors Info & Affiliations Publication: Journal of Clinical Oncology  Volume 43, Number 4_suppl
https://doi.org/10.1200/JCO.2025.43.4_suppl.52



Background: Liver cancer continues to be a significant public health concern, particularly among high-risk groups such as individuals with hepatitis infections, alcohol use disorders, and metabolic diseases. While liver cancer disparities have been well-documented among racial and ethnic minority groups, emerging research highlights significant health inequities within the LGBTQ community, including higher rates of risk factors and limited access to screening and care. This literature review aims to assess the extent of liver cancer disparities within the LGBTQ community and identify gaps in prevention, screening, and treatment.

To Continue Reading:   https://ascopubs.org/doi/10.1200/JCO.2025.43.4_suppl.528

The loss leaves the country with no good way to measure the scale of the viral disease, 
By Helen Branswell April 14, 2025  Senior Writer, Infectious Diseases
An estimated 4 million Americans are infected with hepatitis C, a disease that can go undetected for years. Another 2.4 million people in this country are chronically infected with hepatitis B, which is the leading cause of liver cancer globally. Hepatitis B is preventable, and hepatitis C is curable. But the U.S. capacity to battle these viral scourges has been leveled a devastating blow with the April 1 closure of the country’s premier testing laboratory for viral hepatitis, experts warned. The lab was one of the targets of this month’s Department of Health and Human Services reductions in force, or RIFs, which slashed about 18% of the Centers for Disease Control and Prevention’s workforce and abruptly terminated many of the public health programs conducted by the Atlanta-based agency.The loss of the CDC’s viral hepatitis lab will leave the country with no good way to measure the scale of the problem it faces with these diseases, they suggested, and less able to find the sources of — and put an end to — outbreaks that can be linked to contaminated food, in the case of hepatitis A, or poor infection control procedures in medical facilities, in the case of hepatitis B and C. 
TO CONTINUE READING :https://www.statnews.com/2025/04/14/cdc-hepatitis-lab-closes-rif-outbreak-response/

​Published February 26, 2025 | Originally published on CDC Releases and Announcements

New provisional data from CDC's National Vital Statistics System predict a nearly 24% decline in drug overdose deaths in the United States for the 12 months ending in September 2024, compared to the previous year. This is the most recent national data available and shows a continued steep decline in overdose deaths. Provisional data shows about 87,000 drug overdose deaths from October 2023 to September 2024, down from around 114,000 the previous year. This is the fewest overdose deaths in any 12-month period since June 2020.
"It is unprecedented to see predicted overdose deaths drop by more than 27,000 over a single year," said Allison Arwady, MD, MPH, Director of CDC's National Center for Injury Prevention and Control. "That's more than 70 lives saved every day. CDC's public health investments, our improved data and laboratory systems for overdose response, and our partnerships with public safety colleagues in every state mean that we are more rapidly identifying emerging drug threats and supporting public health prevention and response activities in communities across America."
A common chronic liver condition: when to suspect metabolic dysfunction-associated steatohepatitis (MASH) Novo Nordisk

While this national decline is encouraging news, overdose remains the leading cause of death for Americans aged 18-44, highlighting the importance of sustained efforts to ensure this progress continues. President Trump first declared opioid overdose to be a public health emergency in 2017, a designation that remains in place, and the subsequent public health investments to CDC from Congress have transformed the nation's ability to use data to save lives. In the most recent data, 45 states showed declines in overdose deaths, but five states—Alaska, Montana, Nevada, South Dakota, and Utah—still saw increases in overdose deaths, highlighting the continued need for rapid local data and tailored response. In addition to the large provisional drop in fatal overdoses, we also see smaller decreases in nonfatal overdoses, as measured by emergency department visits for overdose, and welcome continued decreases in self-reported youth substance use.

Multiple factors contribute to the drop in overdose deaths, including widespread, data-driven distribution of naloxone, which is a life-saving medication that can reverse an overdose; better access to evidence-based treatment for substance use disorders; shifts in the illegal drug supply; a resumption of prevention and response after pandemic-related disruptions; and continued investments in prevention and response programs like CDC's flagship Overdose Data to Action (OD2A) program.

TO CONTINUE READING:​  https://www.mdlinx.com/news/cdc-reports-nearly-24-decline-in-us-drug-overdose-deaths/1JeXjAkEoZQlRazX8uObI3?show_order=4&utm_campaign=reg_

ORIGINAL RESEARCH articleFront. Public Health, 22 January 2025
Sec. Children and Health
Volume 12 - 2024 | https://doi.org/10.3389/fpubh.2024.1504678
Farihah Malik1*†Philippa Easterbrook2Giuseppe Indolfi3,4Claire Thorne1

• 1UCL Great Ormond Street Institute of Child Health, University College London, London, United Kingdom
• 2Department of Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland
• 3Meyer Children’s Hospital IRCCS, Florence, Italy
• 4Department Neurofarba, University of Florence, Florence, Italy

Background and aims: There are gaps in knowledge about the values and preferences of healthcare workers (HCW) with respect to treatment of children and adolescents living with chronic hepatitis C (HCV) infection. This study was carried out to identify these values and preferences as part of the evidence required to update World Health Organization (WHO) hepatitis C guidelines.
Methods: An online survey was designed and conducted during August/September 2021. Survey questions were developed to address two key questions about treatment of children and adolescents: who to treat, and which direct acting antiviral (DAA) regimens to use. The survey was circulated by the WHO to nine networks providing care to children and adolescents living with HCV infection, with respondents requested to cascade further within their networks.
Results: A total of 137 individuals from 38 countries responded to the survey. There was a trend toward higher preference for treating children of older age groups; 60% of respondents reported a strong preference for treating (i.e., stating they were very likely or likely to treat) children aged 3 to <6 years, 81 and 95% indicated strong preferences for treating those aged 6 to <12 years and 12 to <18 years, respectively. The most preferred DAA regimens for treatment across all age groups were: sofosbuvir/velpatasvir (SOF/VEL), sofosbuvir/ledipasvir (SOF/LDV), and glecaprevir/pibrentasvir (GLE/PIB). These were also reported to be the most commonly available drug regimens at respondents’ facilities.
Conclusion: This survey provides insights from a heterogenous sample of HCWs from across the world with respect to their expressed priorities and preferences for the treatment of children and adolescents with chronic HCV.

TO CONTINUE READING:
​https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1504678/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE

​By Elizabeth Pratt | Fact-checked by Barbara Bekiesz | Published December 19, 2024
MDLinx

Industry Buzz

• “It is said that medicine is a combination of art and science. [It’s] based on science, but the application of the science for the benefit of the patient, well, that's an art.” — William Schaffner, MD
  
• “They don’t want to interrupt your sleep or private time—they would much rather be in bed themselves. [Remember], it’s neither the emergency doctor’s nor the patient’s fault that some specialist’s expertise is critically needed at an uncivil hour.” — Michael Curry, MD
  

Find more of your peers' perspectives and insights below.
The new year is almost upon us, and there’s never been a better time to brush up on bedside manner.
Sir William Osler, one of the founding professors of Johns Hopkins Hospital, once stated, “The good physician treats the disease; the great physician treats the patient who has the disease.”[1]


Bedside manner is crucial to patient care, and there is always room for improvement. If you want to improve your bedside manner in 2025, here are eight helpful hints.

​TO LEARN MORE:https://www.mdlinx.com/article/want-to-be-a-better-doctor-in-2025-adopt-these-8-habits-for-better-bedside-manner/5G402HZgL10Zpn6FZEPGaW?sh

Summary: In a message to the substance use treatment and public health communities, CDC and SAMHSA leaders highlight the need for and opportunities to increase the provision of HIV and viral hepatitis testing as a part of substance use disorder treatment services.
In a new joint letter, the leaders of the Centers for Disease Control and Prevention (CDC) and the Substance Abuse and Mental Health Services Administration (SAMHSA) encourage the public health and substance use disorder (SUD) treatment communities to increase the number of people with SUD who are tested and treated for HIV and viral hepatitis.

In their message, “Advancing HIV and Viral Hepatitis Testing with Point-of-Care Diagnostics for People with Substance Use Disorder,” Miriam Delphin-Rittmon, PhD, Assistant Secretary for Mental Health and Substance Use, and Mandy Cohen, MD, MPH, Director, Centers for Disease Control and Prevention, discuss the connection between injection drug use and acquisition of hepatitis C, hepatitis B, and HIV, the prevalence of these diseases among people who inject drugs, and CDC’s recommendations for HIV, HCV, and HBV testing for people who inject drugs. While millions of Americans receive SUD treatment services each year, they observe, only a third of the nation’s 15,000 SUD treatment facilities offer HIV, HCV, or HBV testing. They encourage those facilities to integrate HIV and viral hepatitis testing into the services they offer clients and highlight recent advances in point-of-care diagnostics that support such integration, including FDA-approved POC tests for HIV and the recently FDA-cleared fingerstick POC HCV RNA test that enables same-day diagnosis.

​Providing these tests in SUD treatment settings can reduce barriers to accessing them and facilitate initiation of treatment.

https://www.hiv.gov/blog/cdc-and-samhsa-leaders-encourage-hiv-and-viral-hepatitis-testing-in-substance-use-disorder-treatment

Related HIV.gov Blogs

12 December 2024
By Sorcha Daly, Rebecca Bulmer, Vincent Condron, Gary Hind and Matthew Smith

Hepatitis C (HCV) is a blood-borne virus that is most commonly acquired by people who inject drugs. If left untreated, HCV can cause cirrhosis of the liver, liver failure and liver cancer. Unfortunately, due to its most common transmission routes (the sharing of unsterile injecting equipment), hepatitis C is also a stigmatised disease. As such, people who use drugs with a HCV diagnosis face multi-layered stigma, often seen as instruments of contagion, rather than those deserving of care.
It is unsurprising, then, that receiving a positive diagnosis of hepatitis C can have a negative effect on mental health. Diagnosis is associated with lower self-esteem, social isolation, and fears around disclosure and confidentiality breaches. There are also much higher levels of existing mental health difficulties in people diagnosed with HCV. As Dame Carol Black notes in her independent review of drugs in the UK, “trauma (physical, sexual or psychological) and mental ill-health are the drivers and accompaniment” of drug dependency.   
Despite the obvious need for mental and other health services for people with a HCV diagnosis, stigma related to HCV and its transmission routes affect how people interact with health services and can stop people from seeking health care. This not only excludes people from the testing and treatment that could quickly and simply cure HCV, but from accessing mental health and recovery services needed to support the cessation of practices that elevate the risk of acquiring HCV and other blood-borne viruses.

At the Hepatitis C Trust, a group of Peer Researchers have been discussing the use of stigmatising language in policy and research documents and service delivery. We reviewed words and phrases (too many to fit into this blog) used in service delivery, policy and academic papers. Phrases such as ‘drug of choice’ (‘it was never a choice, just a necessity’) and ‘substance use disorder’ (I didn’t use because I was disordered, I just couldn’t deal with the trauma’) were highlighted. As the quotes from our meeting demonstrate, language often misrepresents the reality, perspectives and experiences of people who take and/or are dependent on drugs, leading to policy and practice that fails to meet their needs.

TO CONTINUE READING:​https://www.centreformentalhealth.org.uk/hepatitis-c-and-mental-health-using-peer-support-to-fight-stigma/